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Moderna may be superior to Pfizer against Delta; breakthrough odds rise with time

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Aug 9 (Reuters) - The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19. 

  Moderna's vaccine may be best against Delta 

  The mRNA vaccine from Pfizer and BioNTech may be less effective than Moderna's against the Delta variant of the coronavirus, according to two reports posted on medRxiv on Sunday ahead of peer review. In a study of more than 50,000 patients in the Mayo Clinic Health System https://bit.ly/37Btmhf, researchers found the effectiveness of Moderna's vaccine against infection had dropped to 76% in July - when the Delta variant was predominant - from 86% in early 2021. Over the same period, the effectiveness of the Pfizer/BioNTech vaccine had fallen to 42% from 76%, researchers said. While both vaccines remain effective at preventing COVID hospitalization, a Moderna booster shot may be necessary soon for anyone who got the Pfizer or Moderna vaccines earlier this year, said Dr. Venky Soundararajan of Massachusetts data analytics company nference, who led the Mayo study. 

  In a separate study, elderly nursing home residents in Ontario https://bit.ly/3sb9pHJ produced stronger immune responses - especially to worrisome variants - after the Moderna vaccine than after the Pfizer/BioNTech vaccine. The elderly may need higher vaccine doses, boosters, and other preventative measures, said Anne-Claude Gingras of the Lunenfeld-Tanenbaum Research Institute in Toronto, who led the Canadian study. When asked to comment on both research reports, a Pfizer spokesperson said, "We continue to believe... a third dose booster may be needed within 6 to 12 months after full vaccination to maintain the highest levels of protection." 

  Breakthrough COVID-19 more likely months after vaccination 

  People who received their second dose of the Pfizer/BioNTech vaccine five or more months ago are more likely to test positive for COVID-19 than people who were fully vaccinated less than five months ago, new data suggest. Researchers studied nearly 34,000 fully vaccinated adults in Israel https://bit.ly/3Cucp6O who were tested to see if they had a breakthrough case of COVID-19. Overall, 1.8% tested positive. At all ages, the odds of testing positive were higher when the last vaccine dose was received at least 146 days earlier, the research team reported Thursday on medRxiv ahead of peer review. Among patients older than 60, the odds of a positive test were almost three times higher when at least 146 days had passed since the second dose. Most of the new infections were observed recently, said coauthor Dr. Eugene Merzon of Leumit Health Services in Israel. "Very few patients had required hospitalization, and it is too early to assess the severity of these new infections in terms of hospital admission, need for mechanical ventilation or mortality," he added. "We are planning to continue our research." 

  Ovarian egg sacs not harmed by COVID-19 antibodies 

  The sacs in the ovaries where eggs are stored are not harmed by COVID-19 antibodies, whether those antibodies are the result of infection or vaccination, a small study https://bit.ly/3jFVCoQ suggests. Israeli researchers analyzed fluid from ovarian sacs, or follicles, from 32 women who were having their eggs retrieved to be fertilized by sperm in a test tube. Fourteen women had not been vaccinated against the coronavirus nor infected with it. The others had either recovered from COVID-19 or received the Pfizer/BioNTech mRNA vaccine, and in these two groups the researchers saw antibodies against the virus in follicle fluid. There was no difference among the groups in the follicles' ability to make female sex hormones, nourish and nuture the egg so it will form a good quality embryo, and release the egg during ovulation. There was also no difference in "the rate of good quality embryos" from the eggs retrieved from each patient," said Dr. Yaakov Bentov of Hadassah-Hebrew University Medical Center in Jerusalem, who coauthored a report published on Saturday in Human Reproduction. 

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socrates469bc Collaborator

socrates469bc

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24 minutes ago, The_King said:

Aug 9 (Reuters) - The following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19. 

  Moderna's vaccine may be best against Delta 

  The mRNA vaccine from Pfizer and BioNTech may be less effective than Moderna's against the Delta variant of the coronavirus, according to two reports posted on medRxiv on Sunday ahead of peer review. In a study of more than 50,000 patients in the Mayo Clinic Health System https://bit.ly/37Btmhf, researchers found the effectiveness of Moderna's vaccine against infection had dropped to 76% in July - when the Delta variant was predominant - from 86% in early 2021. Over the same period, the effectiveness of the Pfizer/BioNTech vaccine had fallen to 42% from 76%, researchers said. While both vaccines remain effective at preventing COVID hospitalization, a Moderna booster shot may be necessary soon for anyone who got the Pfizer or Moderna vaccines earlier this year, said Dr. Venky Soundararajan of Massachusetts data analytics company nference, who led the Mayo study. 

  In a separate study, elderly nursing home residents in Ontario https://bit.ly/3sb9pHJ produced stronger immune responses - especially to worrisome variants - after the Moderna vaccine than after the Pfizer/BioNTech vaccine. The elderly may need higher vaccine doses, boosters, and other preventative measures, said Anne-Claude Gingras of the Lunenfeld-Tanenbaum Research Institute in Toronto, who led the Canadian study. When asked to comment on both research reports, a Pfizer spokesperson said, "We continue to believe... a third dose booster may be needed within 6 to 12 months after full vaccination to maintain the highest levels of protection." 

  Breakthrough COVID-19 more likely months after vaccination 

  People who received their second dose of the Pfizer/BioNTech vaccine five or more months ago are more likely to test positive for COVID-19 than people who were fully vaccinated less than five months ago, new data suggest. Researchers studied nearly 34,000 fully vaccinated adults in Israel https://bit.ly/3Cucp6O who were tested to see if they had a breakthrough case of COVID-19. Overall, 1.8% tested positive. At all ages, the odds of testing positive were higher when the last vaccine dose was received at least 146 days earlier, the research team reported Thursday on medRxiv ahead of peer review. Among patients older than 60, the odds of a positive test were almost three times higher when at least 146 days had passed since the second dose. Most of the new infections were observed recently, said coauthor Dr. Eugene Merzon of Leumit Health Services in Israel. "Very few patients had required hospitalization, and it is too early to assess the severity of these new infections in terms of hospital admission, need for mechanical ventilation or mortality," he added. "We are planning to continue our research." 

  Ovarian egg sacs not harmed by COVID-19 antibodies 

  The sacs in the ovaries where eggs are stored are not harmed by COVID-19 antibodies, whether those antibodies are the result of infection or vaccination, a small study https://bit.ly/3jFVCoQ suggests. Israeli researchers analyzed fluid from ovarian sacs, or follicles, from 32 women who were having their eggs retrieved to be fertilized by sperm in a test tube. Fourteen women had not been vaccinated against the coronavirus nor infected with it. The others had either recovered from COVID-19 or received the Pfizer/BioNTech mRNA vaccine, and in these two groups the researchers saw antibodies against the virus in follicle fluid. There was no difference among the groups in the follicles' ability to make female sex hormones, nourish and nuture the egg so it will form a good quality embryo, and release the egg during ovulation. There was also no difference in "the rate of good quality embryos" from the eggs retrieved from each patient," said Dr. Yaakov Bentov of Hadassah-Hebrew University Medical Center in Jerusalem, who coauthored a report published on Saturday in Human Reproduction. 

 

20 minutes ago, chamfer said:

So the booster shot should be moderna....

Wah... then moderna huat big big....

 

based on irl statistics from singapore moh, 3/4 of the newly infected r vaccinated alrdy means the trial data provided by the pharmas r highly questionable liao.

 

cambridge maths master still can tell me vaccination prevents spread.

 

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The_King Rising Star

The_King

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1 minute ago, socrates469bc said:

 

 

based on irl statistics from singapore moh, 3/4 of the newly infected r vaccinated alrdy means the trial data provided by the pharmas r highly questionable liao.

 

cambridge maths master still can tell me vaccination prevents spread.

 

Facebook

 

 

 

there a saying early bird get the worm but i say early worm get eaten by the bird

 

 

 

 

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The_King Rising Star

The_King

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Posted (edited)
15 minutes ago, socrates469bc said:

 

u never hear of intelligence virus meh?????

 

u boast this boast that also no use one.

 

wahahahahaha

 

The Very Intelligent HIV Virus

 

i only hear about the $$$$$$$$ part

 

nv take then need to take an antigen rapid test (ART) twice a week which we need to pay out own ART kits. that the reason why those nv take fast go take sinopharm or sinovax

 

 

 

 

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The_King Rising Star

The_King

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31 minutes ago, XianGe said:

 

Chiu wan tiongland vaccine?

yes, i trust time tested  vax then the first mRNA to be inject into human

 

there no study for the long term effect

 

 

true or not. can go to read at

https://threadreaderapp.com/thread/1419653002818990085.html

 

 

 

@socrates469bc can explain so much better then me

 

why no adverse events from the vax are to be disclosed for a minimum of 10 years.

 

 

 

 

 

Edited by The_King
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socrates469bc Collaborator

socrates469bc

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13 hours ago, XianGe said:

 

Chiu wan tiongland vaccine?

 

13 hours ago, The_King said:

yes, i trust time tested  vax then the first mRNA to be inject into human

 

there no study for the long term effect

 

 

true or not. can go to read at

https://threadreaderapp.com/thread/1419653002818990085.html

 

 

 

@socrates469bc can explain so much better then me

 

why no adverse events from the vax are to be disclosed for a minimum of 10 years.

 

 

 

 

 

 

5 hours ago, Satki said:

Keyword

 

may be

 

 

perios

 

4 hours ago, aaur4man said:

guys i needa take vaxx liao

 

novavax not coming in time for me

 

sinopharm or sinovac and why?

 

mrna is taking part of the rna of the virus to trigger an antibody reaction, thats why faster and safer to produce.

 

disadvantage is trigger over-reaction either due to the shellfish-based lipids or autoimmune response.

 

protein vaccine use deactivated virus to trigger an antibody reaction but slower and more dangerous to produce.

 

advantage is that there is hardly any autoimmune response and the lipid used is usually cow/pig/chicken collagen, so no allergy reaction.

 

but for wuhan-19, all these vaccines r of limited use becos w-19 can mutate lai mutate qu faster than we can mod the vaccines.

 

wahahahahahaha

 

song bo, kumgong humans??????

 

The Very Intelligent HIV Virus

 

 

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The_King Rising Star

The_King

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11 minutes ago, socrates469bc said:

 

 

 

 

mrna is taking part of the rna of the virus to trigger an antibody reaction, thats why faster and safer to produce.

 

disadvantage is trigger over-reaction either due to the shellfish-based lipids or autoimmune response.

 

protein vaccine use deactivated virus to trigger an antibody reaction but slower and more dangerous to produce.

 

advantage is that there is hardly any autoimmune response and the lipid used is usually cow/pig/chicken collagen, so no allergy reaction.

 

but for wuhan-19, all these vaccines r of limited use becos w-19 can mutate lai mutate qu faster than we can mod the vaccines.

 

wahahahahahaha

 

song bo, kumgong humans??????

 

The Very Intelligent HIV Virus

 

 

same me already need to take

 

if you were to take, which one?

 

 

thanks

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socrates469bc

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3 minutes ago, The_King said:

same me already need to take

 

if you were to take, which one?

 

 

thanks

 

i m not guinea pig.

 

alrdy 75% of infected r vaccinated alrdy say how effective the vaccines r liao.

 

wahahahahahhahahah

 

https://www.reuters.com/world/asia-pacific/vaccinated-people-singapore-make-up-three-quarters-recent-covid-19-cases-2021-07-23/

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The_King Rising Star

The_King

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1 hour ago, socrates469bc said:

 

i m not guinea pig.

 

alrdy 75% of infected r vaccinated alrdy say how effective the vaccines r liao.

 

wahahahahahhahahah

 

https://www.reuters.com/world/asia-pacific/vaccinated-people-singapore-make-up-three-quarters-recent-covid-19-cases-2021-07-23/

Me is force by You know from the news.

 

I know you will not take but which one you think the best choice out there

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Standing Birdy Enthusiast

Standing Birdy

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I think the ART test kit is $10-$20 each? Monthly cost will be in low hundreds. If can afford, just pay and stay unvaxed. Consider it as fee for protection against vax effects.

But eventually they will chut more pattern. Easy to make you pay more for "professional" to poke your nose because you cannot be trusted to do a proper poking.

Poke 2x a week dunno nose will spoil boh? They might increase frequency too :haha:

Edited by Standing Birdy
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Bigbird Enthusiast

Bigbird

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"effectiveness of the Pfizer/BioNTech vaccine had fallen to 42% from 76%, researchers said"

 

95%-> 42%

This is soooooo.... misleading! 

 

What's Worse is the side effects list from FDA  is growing. 

 

https://www.fda.gov/media/143557/download?fbclid=IwAR2pR9h1cP3UqtU_wTnlBi51lgVIYBNjd3b4adAZQwlmrMlbKyGFj1qneKI

 

Please sign in or sign up for an account to view this content.

 

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