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not fake news: pfzier's wuhan vaccine may cause immune system over-reaction in some!!!!!!


socrates469bc

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On 1/5/2021 at 9:57 PM, Bigbird said:

 

This shows that all are taking "commercial roll out" as Phase 3 trials! 

 

SG guft C19 vaccine roll out got more pattern then badminton!  Now have Side effect Funds!  This shows how confident they are!

 

COVID-19: Financial aid scheme for those who suffer 'serious adverse events' linked to vaccines – Gan

https://sg.news.yahoo.com/covid-financial-aid-scheme-vaccines-071708423.html

 

Quote

SINGAPORE — A new vaccine injury financial assistance programme will be introduced to help those who suffer “serious adverse events” related to the COVID-19 vaccines being administered in Singapore.

“While we expect few to need this, the programme will give peace of mind to those taking the vaccination,” said Health Minister Gan Kim Yong, who unveiled the scheme during his Ministerial Statement in Parliament on Monday (4 January).

He added that more details on the programme would be provided in due course.

(Full article use link)

 

This Fund is for "death" Hush Hush compensation...  is it? :hehe:

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Every hospital has fund for "hush hush" settlement for negli...

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33 minutes ago, Bigbird said:

What we do and don't know about new Covid-19 mutations

https://www.straitstimes.com/world/europe/what-we-do-and-dont-know-about-new-covid-19-mutations

 

Vaccine Seller will work for new mutations!  Ownselves say Ownselve Good!

 

Prof Says Not sure......  See How aka time will tell ! :hehe:

 

20 minutes ago, The_King said:

i remember this

 

In a vote of confidence for the experts in Singapore who have approved the Pfizer-BioNTech vaccine for pandemic use,  will be getting vaccinated early. This is to show you, especially seniors like me, that we believe the vaccines are safe.

 

 

im still waiting

 

loctors alrdy confirm that one of the spike protein in wuhan has mutated, so means that any vaccine using mRNA technology has theoretically been rendered useless.

 

https://www.cnbc.com/2021/01/05/south-africa-covid-variant-appears-to-obviate-antibody-drugs-dr-scott-gottlieb-says.html

 

“The new variant has mutated a part of the spike protein that our antibodies bind to, to try to clear the virus itself, so this is concerning,” Gottlieb said.

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On 12/19/2020 at 4:41 PM, XianGe said:

Wait for pinky to get his jab

 

29 minutes ago, The_King said:

i remember this

 

In a vote of confidence for the experts in Singapore who have approved the Pfizer-BioNTech vaccine for pandemic use,  will be getting vaccinated early. This is to show you, especially seniors like me, that we believe the vaccines are safe.

 

 

im still waiting

 

tiagong ah din has went for vaccine injection but npnt!!!!!!

 

https://www.theedgemarkets.com/article/pm-muhyiddin-be-among-first-receive-covid19-vaccine-injections-followed-frontliners-highrisk

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22 hours ago, socrates469bc said:

 

You should know our Xiaxuay Army Gen style, when fire fight all hide in bunker/HQ.  Let the minions die!

 

When over, then the come out to show their Xiaxuay face. 

 

Therefore, their Lives is more Important than Yours!  :hehe:

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On 12/15/2020 at 8:39 PM, The_King said:

later like the token method, token is not compulsory but if you need token to go to mall, food center etc..... token can mean the app also, either one

 

vaccines not compulsory but if you never take then if anything happen you pay full medical fee, not allow to enter places with many ppl

 i am right. follow the token method. make your life so tough you got no choice but to takeand it still volunteer

 

 

 

https://www.channelnewsasia.com/news/singapore/covid-19-vaccine-testing-requirements-lawrence-wong-13912834

 

 

 

 

More frequent tests, additional requirements likely for those who do not take COVID-19 vaccine

 

 

SINGAPORE: Individuals who choose not to take the COVID-19 vaccine may need to go through “more frequent testing”, said Minister for Education Lawrence Wong on Thursday (Jan 7).  

In an interview on CNA’s Talking Point, the co-chair of the COVID-19 multi-ministry task force spoke of "tangible benefits" for those who choose to get vaccine shots.

 

“It may well be, if the data validates all the hypotheses, that transmission risk can be significantly reduced. It may well be that travellers coming back need not serve SHN (stay-home notice) or will serve a shorter SHN. So those will be the benefits of getting a vaccination besides the fact that you are protecting yourself and your loved ones,” he added. 

“There will be these tangible benefits and those who choose not to be vaccinated, well, then you have to live with more frequent tests, you have to live with quarantine, you have to live with all of these other additional requirements.” 

 

Mr Wong also explained why the vaccine made by the Chinese biopharmaceutical company Sinovac was picked as one of the three vaccines to be used in Singapore. The vaccine, named CoronaVac, is not widely used and no conclusive studies have been conducted on it yet.

 

The Government convened an expert panel to look at making early purchases of vaccines “as early as April”, Mr Wong said. 

 

“We have to make early bets in order for Singapore to be near the front of the queue for vaccines. And that's what is happening today.” 

At the time, there was no clinical data or “full-fledged information” available from any vaccine company, said Mr Wong. 

 

With only "very early stage clinical information" available, the committee and experts narrowed down the selections to 35 vaccine candidates. They eventually decided on the three vaccines - Moderna, Pfizer-BioNTech and Sinovac - based on safety and effectiveness based on the preliminary data that was available then, he added. 

“And that's the three that we have made advanced purchases for, with the aim of building a diversified portfolio of vaccines that will be safe and effective for use in Singapore,” said Mr Wong.

When asked by Talking Point host Steve Chia if this approach by Singapore could be characterised as "hedging (its) chances", Mr Wong replied: "Very much so."

 

 

According to the Economic Development Board (EDB), the vaccine panel made its first advance purchase agreement with Moderna in June, securing it with a downpayment. In August, it bought the Sinovac vaccine and was in advance talks with Pfizer-BioNTech.

Singapore’s Health Sciences Authority (HSA) eventually approved the Pfizer-BioNTech vaccine first. Prime Minister Lee Hsien Loong announced in a televised address on Dec 15, 2020 that the first shipment would arrive by the end of December, with other vaccines expected in the coming months. 

The first doses of the vaccines were rolled out to staff at the National Centre for Infectious Diseases (NCID) on Dec 30, 2020. 

 

The panel intends to continue to see whether it can make further purchases to add to the vaccine portfolio, said Mr Wong. 

“That's our overall approach. It's not to make a single bet, we know that we've made some early bets, some may turn out positive as I think Pfizer has now been authorised, Moderna looks like it's going to be, it has been approved in America,” he added.  

“We are looking at the data, we will await that data full data from Sinovac and then the process will continue for other vaccine candidates.”

VACCINE SAFETY 

The Moderna and Pfizer-BioNTech vaccines use the new messenger RNA (mRNA) technology, while Sinovac is a traditional inactivated virus vaccine.

mRNA vaccines teach our cells to make a protein that triggers an immune response inside our bodies, said director of communicable diseases at the Ministry of Health (MOH) Associate Professor Vernon Lee. This is different from traditional vaccines that put a weakened or inactivated germ into our bodies.

“This is basically the key - the actual mRNA degrades very quickly in the body, so body temperature will only remain for about 48 hours. And thereafter, there's no additional component of the vaccine that remains in the individual,” added Assoc Prof Lee, who was also speaking on Talking Point.

 

 

Although the Pfizer-BioNTech vaccine is the only one approved so far, as additional vaccines come onboard, there will be some vaccines that can or cannot be used in certain subpopulations, he added.

For example, the Pfizer-BioNTech vaccine cannot be used in people who have severe allergic reactions or a history of anaphylaxis, said Assoc Prof Lee. For now, children under 16, pregnant women and individuals who are severely immunocompromised are also excluded from using the Pfizer-BioNTech vaccine.

“Other vaccines might be able to be used in different populations. So we need to wait for more information, and it is which vaccine is more ... applicable or relevant to that particular population if it's offered, we will encourage people to get that vaccine,” he added. 

The third guest on Talking Point, Associate Professor Benjamin Ong, senior vice president (Health Education & Resources) at the National University of Singapore (NUS), said the data for the Pfizer-BioNTech vaccine is “most complete”, and experts are “confident enough” to recommend its use in Singapore’s setting. 

CHOICE OF VACCINE

On the subject of whether people would be allowed to choose their vaccine, Mr Wong said that the Pfizer-BioNTech and Moderna vaccines worked similarly, and efficacy rates from evidence around the world were “all about the same”. 

 

 

“So really, there's not much to differentiate between these two vaccines. I think at this point in time, we have Pfizer only, there's nothing to choose from. So let's go with Pfizer, get people vaccinated on the Pfizer vaccine,” he added. 

“If later on other vaccines are authorised, be it Moderna or Sinovac, then we have to think about whether choice may be extended. Or perhaps some vaccines work better for certain sub-segments of the population, and then we might allocate vaccines differently as well.”

VIRUS MUTATIONS

When asked about the new strain of COVID-19 that surfaced after the Pfizer-BioNTech and Moderna vaccines were approved around the world, Assoc Profs Ong and Lee said mutations occur “all the time”, and are part of "natural evolution”. 

Prof Lee likened the mutations to a car getting a different licence plate or colour. 

“The same make, same model, different licence plate, we see many of them all around the time. And sometimes you might have a car with new tires, it might be a bit more efficient, move faster, and so on, but it's still the same make,” he added. 

“At this point, there's no evidence that it (the virus) has changed to another make, another model, another brand. And we, of course, will be looking out for different strains, different variants that occur all the time.” 

From the mutations that have been studied so far, it seems like the vaccines “probably would still work”, said Assoc Prof Ong, adding that this is being actively tested. 

“The areas that pertain to the spike protein, for example, are conserved. So from the basic scientific principles, it should still work. And we will know very soon because more than two, three million people now in the UK in the US have received a vaccine. And if it is not going to work, in the next few weeks to months, we will know,” he said. 

The variants that have been reported are only those that have been detected, and there may be others that have yet to surface, said Assoc Prof Lee. 

“Actually what's important is in addition to the vaccine, we have a very strong border, you know, control regime, plus all the same management measures wearing of masks or contact tracing,” he added. 

 

 

UNVACCINATED INDIVIDUALS STILL SUSCEPTIBLE

Acknowledging that many people hope to return to a pre-pandemic normal, Mr Wong said that even in a post-COVID-19 world, there would be pandemics with more virulent diseases that arise in the future. 

“I think rather than thinking about let’s go back to life before COVID, I think we should be thinking now about what are the things that we have done during this period that really ought to be permanently part of our new daily routines,” he added. 

“And how can we raise our levels of defences, our levels of protection, our levels of hygiene so that we can be more prepared and more resilient in the future?” 

Assoc Prof Lee also stressed that individuals who do not get vaccinated are “still susceptible” to being infected with COVID-19. 

“Even if we reach that sort of herd immunity or collective protection level, it does not mean that there will be no cases and that’s the same for all other infectious diseases. And the risk of cases occurring in Singapore is not just what we do here but what’s happening in the rest of the world,” he said, adding that an open economy, travel and trade would result in imported cases. 

“If we are not vaccinated, every single individual who is not vaccinated, is another naive susceptible individual who then can get infected by those diseases. To protect yourself, you should get vaccinated and then there’s the other benefit of protecting your loved ones and those around you,” said Assoc Prof Lee. 

“It is very important for that reason because even if we have a high vaccination coverage, it does not mean no disease. It is not possible to wipe COVID-19 from the face of the earth. We’re going to see this recurring from time to time, so it is important for that personal protection reason.” 

Source: CNA/hw(ac)

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https://www.asiaone.com/world/us-officials-report-more-severe-allergic-reactions-covid-19-vaccines

 

 

 

US officials report more severe allergic reactions to Covid-19 vaccines

 

 

 

The US Centers for Disease Control and Prevention (CDC) said on Wednesday it is carefully monitoring allergic reactions to the coronavirus vaccines from Pfizer Inc and Moderna Inc and urged individuals who had a serious reaction not to get the second dose.

In a conference call with reporters, the US public health agency said allergic reactions are occurring at a rate of 11.1 per 1 million vaccinations. That compared with flu vaccines, in which such reactions occur at a rate of 1.3 per 1 million shots.

The severe reactions are still “exceedingly rare,” they said, stressing the need for people to get vaccinated when the shots become available to them, given the threat of death and serious disease from the coronavirus that has already claimed more than 357,000 lives in the United States alone.

The CDC said it is monitoring allergic reaction incidents closely and plans to post weekly updates on its website.

The agency is also urging that venues that deliver the vaccine be prepared not only to recognise serious allergic reactions, known as anaphylaxis, but be trained on how to treat them and recognise when individuals need to be referred to hospitals for additional care.

CDC officials said 28 people who received the coronavirus vaccine developed by Pfizer and BioNTech had severe allergic reactions.

They also noted one case of anaphylaxis, which can cause throat swelling and breathing difficulty, after an individual received Moderna’s vaccine.

 

Officials attributed the difference largely to the fact that the Pfizer/BioNTech vaccine was authorised earlier than the Moderna shot, and said the precautions apply to both.

A study published on Wednesday in the CDC’s weekly report on death and disease looking at cases between Dec. 14 and Dec. 23, identified 21 cases of anaphylaxis after the administration of 1,893,360 doses of the Pfizer/BioNTech vaccine.

Of these, 71 per cent occurred within the first 15 minutes after vaccine administration.

Britain’s medical regulator has said that anyone with a history of anaphylaxis, or severe allergic reactions to a medicine or food, should not be given the Pfizer/BioNTech vaccine.

 

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Scientists are monitoring a coronavirus mutation that could affect the strength of vaccines

By Andrew Joseph @DrewQJoseph

January 7, 2021

 

Quote

As scientists try to track the spread of a new, more infectious coronavirus variant around the world — finding more cases in the United States and elsewhere this week — they are also keeping an eye on a different mutation with potentially greater implications for how well Covid-19 vaccines work.

The mutation, identified in a variant first seen in South Africa and separately seen in another variant in Brazil, changes a part of the virus that your immune system’s antibodies get trained to recognize after you’ve been infected or vaccinated. Lab studies show that the change could make people’s antibodies less effective at neutralizing the virus. The mutation seems to help the virus disguise part of its signature appearance, so the pathogen might have an easier time slipping past immune protection.

It’s not that the mutation will render existing vaccines useless, scientists stress. The vaccines authorized so far and those in development produce what’s called a polyclonal response, generating numerous antibodies that home in on different parts of the virus. Changes to any of those target sites raise the possibility that the vaccines would be less effective, not that they won’t work at all.

 

With one mutation or even three mutations, it’s expected the antibodies will still recognize this variant, though they might not recognize it as well as other variants,” said Ramón Lorenzo-Redondo, a molecular virologist at Northwestern University’s Feinberg School of Medicine.

Essentially, the mutation is getting attention because it appears more likely to have some effect on vaccines than other mutations that have emerged, though scientists are still trying to test that hypothesis. The more contagious variant raising global alarms, which was first seen in the United Kingdom and is referred to as B.1.1.7, is not thought to have mutations that will greatly affect vaccines, the evidence so far indicates.

“We need to be monitoring for these mutations,” said Jesse Bloom, an evolutionary virologist at Fred Hutchinson Cancer Research Center, who with colleagues published a paper about this specific mutation, known as E484K, this week.

https://www.statnews.com/2021/01/07/coronavirus-mutation-vaccine-strength/

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https://blogs.bmj.com/bmj/2021/01/04/peter-doshi-pfizer-and-modernas-95-effective-vaccines-we-need-more-details-and-the-raw-data/

QUOTE

All attention has focused on the dramatic efficacy results: Pfizer reported 170 PCR confirmed covid-19 cases, split 8 to 162 between vaccine and placebo groups. But these numbers were dwarfed by a category of disease called “suspected covid-19”—those with symptomatic covid-19 that were not PCR confirmed. According to FDA’s report on Pfizer’s vaccine, there were “3410 total cases of suspected, but unconfirmed covid-19 in the overall study population, 1594 occurred in the vaccine group vs. 1816 in the placebo group.”

With 20 times more suspected than confirmed cases, this category of disease cannot be ignored simply because there was no positive PCR test result. Indeed this makes it all the more urgent to understand. A rough estimate of vaccine efficacy against developing covid-19 symptoms, with or without a positive PCR test result, would be a relative risk reduction of 19% (see footnote)—far below the 50% effectiveness threshold for authorization set by regulators. Even after removing cases occurring within 7 days of vaccination (409 on Pfizer’s vaccine vs. 287 on placebo), which should include the majority of symptoms due to short-term vaccine reactogenicity, vaccine efficacy remains low: 29%

 

 

 

https://www.scmp.com/news/china/science/article/3117471/coronavirus-brazil-reports-more-modest-504-cent-efficacy-chinas

QUOTE

Phase 3 trial data for the US-based Pfizer-BioNTech Covid-19 vaccine, for example, gives a 95 per cent efficacy rate. However, out of the 44,000 volunteers there were 3,410 participants who displayed Covid-19 symptoms but were not tested, according to a US Food and Drug Administration report. In the unlikely event that all these participants tested positive, the total efficacy rate would drop to below 30 per cent.

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This is what the Pfizer covid19 vaccine has done to my Mom. Everyone please pray for her. She was admitted to the hospital last. And be cautious about taking the vaccine. I'm sure it is good for some people but you need to think about is this vaccine worth taking? It's not for me.
Update: 1-11-21 my mom had a bad night last night but today was a little better for her. They still don't know how to treat this problem. MRI results came back good today
Update#2 1-11-21
I guess we spoke too soon. Mom just had another serious episode and she thinks it's getting worse when the shakes come. I'll try to add the video she just sent me. Sorry for the bad quality iPhone to Android doesn't do well through texts
Update 1-12-21
Mom Is getting even worse today and still don't have any answers from doctors as to how to fix this. Please pray for her I can't stand to see my mom this way it makes me want to cry knowing I can't do anything to help her. Please don't take the covid19 vaccine. I'm adding a 3rd video that she just sent me.
Edited by The_King
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19 hours ago, The_King said:

 

https://www.scmp.com/news/china/science/article/3117471/coronavirus-brazil-reports-more-modest-504-cent-efficacy-chinas

QUOTE

Phase 3 trial data for the US-based Pfizer-BioNTech Covid-19 vaccine, for example, gives a 95 per cent efficacy rate. However, out of the 44,000 volunteers there were 3,410 participants who displayed Covid-19 symptoms but were not tested, according to a US Food and Drug Administration report. In the unlikely event that all these participants tested positive, the total efficacy rate would drop to below 30 per cent.

 

thats why nothing can replace data from monkey or human trials.

 

all these clinical trials only accurately measure for possible side-effect in large population sample if carried out in unbiased random sample.

 

these clinical trials cannot measure how effective a vaccine is when a subject is deliberately exposed.

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On 1/13/2021 at 4:03 PM, The_King said:

2 million ppl injection sinovac only 1 million is protected

 

In this circumstances, Aviation Consultants will say "This is just like saying 50% the time your aircraft will stop working when u are flying, we just dont know when"! :hehe:

 

11 hours ago, socrates469bc said:

 

thats why nothing can replace data from monkey or human trials.

 

all these clinical trials only accurately measure for possible side-effect in large population sample if carried out in unbiased random sample.

 

these clinical trials cannot measure how effective a vaccine is when a subject is deliberately exposed.

 

Processes are made for a reason!

 

I am sure Nobody wants to fly in a Aircraft that is build in 1/10 of the actual time needed! 

 

I dont even want to think what kind of test can be done & mitigated in such a short period! 

 

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My issue is not weather the vaccine will work, it's about whether it's SAFE a not?

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2 hours ago, The_King said:

 

Non Chinese News Sites

https://www.washingtonpost.com/world/europe/norway-adjusts-advice-after-vaccine-deaths-but-isnt-alarmed/2021/01/15/d69cfa84-572d-11eb-acc5-92d2819a1ccb_story.html

 

 

NORWAY changes its vaccine guidelines after the deaths of 23 people who received the vaccine

 

https://www.euroweeklynews.com/2021/01/15/norway-changes-vaccine-guidelines-after-23-deaths/

Norway has taken the lead in changing its guidelines for people receiving the Covid-19 vaccine after 23 people have lost their lives shortly after receiving the jab. Norwegian authorities have confirmed to national new outlet The Epoch Times that, of the 23 people who have died, 13 of the deaths “could have been caused, directly, by the secondary effects of the vaccines.”

 

The negative reactions to the Pfizer/BioNTech vaccine have prompted spokesperson for the Norwegian Medicines Agency, Steinar Madsen, to announce a change to official guidance on who should receive the jab. According to Madsen, “people in weak health probably should not be vaccinated.”

_____________________________________

 

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28 minutes ago, The_King said:

 

got a kgk recently told me that the vaccines r effective and safe,  which will enable the economy to re-open.

 

i told him i wont be taking becos of allergy and high blood pressure b4 adding that at least 30% of the population have either or both like, so they also wont be taking.

 

i didnt tell him that the vaccines thus far r ineffective so as not to depress him further.

 

wahahahahhahahahah

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3 minutes ago, socrates469bc said:

 

got a kgk recently told me that the vaccines r effective and safe,  which will enable the economy to re-open.

 

i told him i wont be taking becos of allergy and high blood pressure b4 adding that at least 30% of the population have either or both like, so they also wont be taking.

 

i didnt tell him that the vaccines thus far r ineffective so as not to depress him further.

 

wahahahahhahahahah

 

that kgk is the smartest person on earth. so smart no one care

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Previous coronavirus infection may offer less protection from new variant

January 19, 2021

published at 9:43 AMReuters

JOHANNESBURG - Previous infection with the coronavirus may offer less protection against the new variant first identified in South Africa, scientists said on Monday, although they hope that vaccines will still work.

Studies also found that the new variant binds more strongly and readily to human cells. That helps explain why it seems to be spreading around 50 per cent quicker than previous versions, leading South African epidemiologist Salim Abdool Karim said.

 

The 501Y.V2 variant was identified by South African genomics experts late last year. It has been the main driver of a second wave of national Covid-19 infections, which hit a new daily peak above 21,000 cases earlier this month.

It is one of several new variants found in recent months, including others first discovered in England and Brazil, which scientists worry are hastening the spread of Covid-19.

 

Convalescent serum studies suggest natural antibodies are less effective,” Abdool Karim said, introducing the research, “(but) current data suggest the new variant is not more severe.”

British scientists and politicians have expressed concern that vaccines currently being deployed or in development could be less effective against the variant.

Scientists speaking at the virtual panel on Monday said there was not yet a clear answer to that question and that studies were continuing.

“We have reason to be concerned because the virus has found a way to escape from previous antibodies,” Alex Sigal, a virologist at the Africa Health Research Institute, said.

“The world has underestimated this virus. This virus can evolve, it ... is adapting to us.”

 

Earlier, South African researchers said that since vaccines induce a broad immune response it was unlikely that the mutations in the spike protein of the variant would completely negate their effect.

The researchers reiterated that notion on Monday.

“Our immune systems are extraordinarily clever,” Willem Hanekom, one of the team, said. “There may be compensation through other arms of the immune system that allow vaccines to still work”.

The 501Y.V2 variant has spread to nations in Europe, Asia and the Americas, as well as several other African countries, causing some states to impose restrictions on travel to and from South Africa.

 

https://www.asiaone.com/world/previous-coronavirus-infection-may-offer-less-protection-new-variant

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10 hours ago, The_King said:

 

 

now moderna wants to check for allergy.

 

https://www.reuters.com/article/us-health-coronavirus-moderna/moderna-says-possible-allergic-reactions-to-covid-19-vaccine-under-investigation-idUSKBN29O2C5

 

nb, alrdy said at the very beginning if phrase 3 clinical trial data not released for independent verification sure will have problem but no one believe me becos limpeh me no medical phd.

 

limpeh me got degree in statistics alrdy pawn moh gao gao liao, so mai play play.

 

cna, pls notice me!!!!!

 

https://www.channelnewsasia.com/news/singapore/covid-19-vaccine-moderna-supply-agreement-moh-13775604

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Thousands of Israelis test POSITIVE for Covid-19 despite receiving Pfizer/BioNTech jab


More than 12,400 people in Israel have tested positive for coronavirus after being vaccinated with the Pfizer/BioNTech jab, including 69 who had received their second dose, the country's Health Ministry said.
Some 189,000 people were tested for Covid-19 after being vaccinated, with 6.6 percent getting a positive result, according to ministry data reported by Israeli outlets. The majority were apparently infected shortly after receiving the first jab of the two-part vaccine – a period when the inoculation isn't expected to have kicked in yet.

However, 1,410 people tested positive two weeks after their first injection, by which time partial immunity should have already taken effect.

https://www.rt.com/news/513139-israel-pfizer-vaccine-coronavirus/

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