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Triple Mutation Strain Detected in 4 Indian States


The_King

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New Delhi: India is currently in the middle of a ferocious second Covid wave, overtaking Brazil to become the second-most affected country in the world. With second wave of Covid wreaking havoc in India, a third mutation in this B.1.617 strain has now been identified in at least 4 states, spiraling as a major cause of concern. Two of these triple-mutant varieties have been found in samples collected from Maharashtra, Delhi, West Bengal and Chhattisgarh, and this might aggravate India’s Covid crisis further. According to an Indian Express report, sources said the Health Ministry was last week briefed about the possibility of a double mutant variant developing another significant mutation and becoming a ‘triple-mutant.’ The report further said that West Bengal seems to be becoming the hotspot for such mutations and the new triple mutant could make the virus even more capable of evading human immune response.

 

 

“It (the double mutant) was detected way back. It was found again in November and December. By February, this variant is exploding, almost coinciding with the surge in Maharashtra. The discovery should have been acted upon immediately. But nothing happened. Now we are fire-fighting,” a scientist told the publication.

What is a Mutant Strain?

Simply put, just like all viruses, the coronavirus keeps changing as it passes from one person to another. The Covid-19 virus has been mutating ever since it emerged. During replication, a virus often undergoes genetic mutations that may create what are called variants. Variants with distinctly different physical characteristics may be co-termed a strain.

 

Thankfully, a lot of these mutations aren’t dangerous and don’t alter the way the virus behaves. However, some mutations trigger changes in the spike protein that the virus uses to latch on to and enter human cells, a report by BBC said. A triple mutant refers to variants which have three different strains that have combined together to form a new variant. As of now, multiple SARS-CoV-2 variants are circulating globally and a triple mutant strain could be the next challenge for India.

 

 

https://www.india.com/health/triple-mutation-strain-detected-in-4-indian-states-why-mutant-strain-is-dangerous-needs-effective-monitoring-explained-4601793/

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